S. Pickelmann et al., EFFECTS OF THE MODIFIED HEMOGLOBIN SOLUTI ON DCLHB(TM) ON THE MICROCIRCULATION OF STRIATED SKIN MUSCLE AFTER ISCHEMIA-REPERFUSION, Langenbecks Archiv fur Chirurgie, 1996, pp. 97-100
The results of the current study indicate that the presence of Diaspir
in Crosslinked Hemoglobin (DCLHb(TM)) in blood plasma does not exacerb
ate reperfusion-injury in postischemic tissue. The reduction of the nu
mber of adhering leukocytes to postcapillary venular endothelial cells
as well as the reduction of macromolecular leakage with subsequent ex
travasation of plasma to the perivascular tissue and edema formation f
avour the treatment of reperfusion-injury with DCLHb(TM).