Objective. To evaluate arthroscopic findings as a potential measuremen
t of severity and outcome of chondropathy. Methods. 110 patients with
knee osteoarthritis (OA) were included in a cross sectional study and
41 of them in a one year longitudinal study. The evaluation of OA perf
ormed once in the cross sectional study and twice (at entry and after
one year) in the longitudinal study, included clinical, radiologic:al
and arthroscopic variables evaluating disease activity and severity. A
rthroscopy was performed under local anesthesia in an outpatient proce
dure using a small arthroscope. Chondropathy was evaluated by the over
all assessment of the investigator by visual analog scale and the Soci
ete Francaise d'Arthroscopie (SFA) scoring and grading systems, which
represent a composite index taking into account depth, size, and local
ization of the articular cartilage lesions. Results. The intrinsic val
idity of the arthroscopic variables was suggested by highly significan
t correlation (R(2) = 80-85%) between the overall assessment of the in
vestigator and the SFA systems. There was also highly significant corr
elation (p < 0.01) between the arthroscopic and radiological variables
. Intraobserver reliability of the arthroscopic quantification of chon
dropathy was better than interobserver reliability. In the cross secti
onal study, severity of chondropathy correlated with both age and body
mass index. In the longitudinal study there was statistically signifi
cant worsening in tile severity of chondropathy and statistically sign
ificant correlation between the changes in the severity of chondropath
y and changes in functional impairment. Conclusion. We conclude that a
rthroscopy might be considered a relevant measurement of OA outcome fo
r research purposes.