GOODPASTURES DISEASE AND ALPORTS SYNDROMES

Authors
Citation
An. Turner et Aj. Rees, GOODPASTURES DISEASE AND ALPORTS SYNDROMES, Annual review of medicine, 47, 1996, pp. 377-386
Citations number
34
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00664219
Volume
47
Year of publication
1996
Pages
377 - 386
Database
ISI
SICI code
0066-4219(1996)47:<377:GDAAS>2.0.ZU;2-B
Abstract
Goodpasture's, or anti-glomerular basement membrane, disease is an unc ommon, usually severe disease caused by autoimmunity to a component of certain basement membranes. Alport's syndrome is an inherited, degene rative disorder that affects specific basement membranes. The two are linked by the involvement of type-IV collagen (basement membrane colla gen) in their pathogenesis.