SYNTHESIS OF A NEW TYPE OF BENT HETEROCYCLIC BENZIMIDAZOLO-PYRIDAZINONES

Authors
JONAS R PRUCHER H WURZIGER H
Citation
R. Jonas et al., SYNTHESIS OF A NEW TYPE OF BENT HETEROCYCLIC BENZIMIDAZOLO-PYRIDAZINONES, European journal of medicinal chemistry, 28(2), 1993, pp. 141-148
Citations number
17
Categorie Soggetti
Chemistry Medicinal
Journal title
European journal of medicinal chemistry → ACNP
ISSN journal
02235234
Volume
28
Issue
2
Year of publication
1993
Pages
141 - 148
Database
ISI
SICI code
0223-5234(1993)28:2<141:SOANTO>2.0.ZU;2-W
Abstract
The synthesis of some new heterocyclic benzimidazolo-pyridazinones sta rting from 2,1,3-benzothiadiazole-4-carboxaldehyde 2 is described. Bio logical evaluation of all new compounds proved them to be inhibitors o f phosphodiesterase III with no marked positive inotropic effects.