KAPOSIS DISEASE AND SARCOIDOSIS

A human immunodeficiency virus (HIV) antibody-negative 65 year old wom an was treated with corticosteroids for 7 yrs because of bilateral mel ds. One year after the beginning of corticosteroid treatment, erythema tous skin lesions appeared on the legs. Eight years after the diagnosi s of uveitis, gastric and bronchial biopsies revealed noncaseating epi thelioid cell granulomas, whilst a cutaneous biopsy showed Kaposi's di sease. Sarcoidosis-associated alteration of immune regulation and cort icosteroid therapy may have promoted the development of disease.