Fm. Ferrante, PRINCIPLES OF OPIOID PHARMACOTHERAPY - PRACTICAL IMPLICATIONS OF BASIC MECHANISMS, Journal of pain and symptom management, 11(5), 1996, pp. 265-273
Opioids form the cornerstone of the pharmacologic armamentarium for th
e treatment of pain. Despite their long history of use, much confusion
and misperception still surrounds their use. This short review will f
ocus on pharmacodynamic and physiologic considerations in the clinical
use of oral and parenteral opioids.