ASYMMETRIC BIS(ALKOXYCARBONYLATION) REACTION OF HOMOALLYLIC ALCOHOLS CATALYZED BY PALLADIUM IN THE PRESENCE OF CU(I) TRIFLATE USING THE CHIRAL BIOXAZOLINE LIGAND

Authors
UKAJI Y MIYAMOTO M MIKUNI M TAKEUCHI S INOMATA K
Citation
Y. Ukaji et al., ASYMMETRIC BIS(ALKOXYCARBONYLATION) REACTION OF HOMOALLYLIC ALCOHOLS CATALYZED BY PALLADIUM IN THE PRESENCE OF CU(I) TRIFLATE USING THE CHIRAL BIOXAZOLINE LIGAND, Bulletin of the Chemical Society of Japan, 69(3), 1996, pp. 735-742
Citations number
27
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Chemical Society of Japan → ACNP
ISSN journal
00092673
Volume
69
Issue
3
Year of publication
1996
Pages
735 - 742
Database
ISI
SICI code
0009-2673(1996)69:3<735:ABROHA>2.0.ZU;2-3
Abstract
Palladium-catalyzed asymmetric intra- and intermolecular bis(alkoxycar bonylation) reactions of homoallylic alcohols in the presence of coppe r(I) triflate were achieved by using the chiral bioxazoline ligand, 4, 4'-dibenzyl-4,4',5,5'-tetrahydro-2,2'-bioxazole, under normal pressure of carbon monoxide and oxygen at 25 degrees C to give the correspondi ng optically active gamma-butyrolactones in 19-65% ee.