ASPERGILLOSIS OF THE SPHENOID SINUS - PRESENTATION AS A PITUITARY MASS AND POSTOPERATIVE GA-67 IMAGING

Invasive aspergillosis of the paranasal sinuses is an uncommon, but we ll-recognized, form of fungal infection. We describe an elderly female patient with invasive aspergillosis of the sphenoid sinus and associa ted osteomyelitis of the skull base, with clinical presentation as a p ituitary mass. Postoperative gallium scan showed intense uptake in the sphenoid sinus, which resolved after treatment with amphotericin-B. T his case demonstrates some of the pathologic and clinical features of invasive aspergillosis and suggests a potential role for gallium-67 im aging in monitoring clinical response to therapy.