TWO CASES OF paraganglioma arising from the parasellar region are pres
ented. Both occurred in middle-aged women who sought treatment of head
aches but who had no endocrinological dysfunction; one case was associ
ated with ophthalmoplegia from cavernous sinus involvement. Diagnosis
in both cases was confirmed by typical histological appearance and cyt
ochemical demonstration of immunoreactive chromogranin in tumor cells.
The pathological features and possible pathogenesis of parasellar par
agangliomas are discussed.