BLUE RUBBER BLEB NEVUS SYNDROME

A 26-yr-old man was admitted with malaise and melena, During the physi cal examination, six hemangiomas were spotted on the skin, and laborat ory evaluations proved the existence of severe iron deficiency anemia (Hb 2.9 g/dl). Upper endoscopy and small bowel follow-through revealed no pathology. Colonoscopy documented the presence of a blue-red caver nous hemangioma, 1 cm in diameter, at the splenic flexura, The skin an d colonic lesions were typical; thus, blwue-rubber-bleb-nevus syndrome was diagnosed. The patient was given blood transfusions followed by o ral iron supplementation. He refused further evaluation or surgery and is still fine after a follow-up period of 6 months. Here, we present a discussion of this case, together with a detailed review of the lite rature.