OXAZOLO[4,5-B]PYRIDINES - REGIOCHEMISTRY OF ELECTROPHILIC SUBSTITUTION IN THE 2-DIETHYLAMINOOXAZOLO[4,5-B]PYRIDINE SYSTEM - SYNTHESIS OF 6-SUBSTITUTED DERIVATIVES

Authors
LEVER OW WERBLOOD HM RUSSELL RK
Citation
Ow. Lever et al., OXAZOLO[4,5-B]PYRIDINES - REGIOCHEMISTRY OF ELECTROPHILIC SUBSTITUTION IN THE 2-DIETHYLAMINOOXAZOLO[4,5-B]PYRIDINE SYSTEM - SYNTHESIS OF 6-SUBSTITUTED DERIVATIVES, Synthetic communications, 23(9), 1993, pp. 1315-1320
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
23
Issue
9
Year of publication
1993
Pages
1315 - 1320
Database
ISI
SICI code
0039-7911(1993)23:9<1315:O-ROES>2.0.ZU;2-S
Abstract
Electrophilic substitution occurs regiospecifically at C-6 in the 2-di ethylaminooxazolo-[4,5-b]pyridine system to provide 6-nitro and 6-halo derivatives. The 6-nitro compound is readily convened to the 6-amino derivative which may be further elaborated by standard methods to prov ide more complex derivatives.