Ta. Siller et al., EFFICACY AND COST CONSIDERATIONS OF INTRAOPERATIVE AUTOLOGOUS TRANSFUSION IN SPINAL-FUSION FOR IDIOPATHIC SCOLIOSIS WITH PREDEPOSITED BLOOD, Spine (Philadelphia, Pa. 1976), 21(7), 1996, pp. 848-852
Study Design. One hundred five patients with adolescent idiopathic sco
liosis who underwent posterior spinal instrumentation and fusion with
predeposited autologous blood, with or without intraoperative autologo
us transfusion, were reviewed. Objective. To determine the benefit/non
benefit of intraoperative autologous transfusion in diminishing the ne
ed for homologous blood and influencing postoperative hematocrit value
s in healthy adolescents undergoing spinal fusion for scoliosis. Summa
ry of Background Data. A steady increase in the use of intraoperative
autologous transfusion in recent years has occurred without guidelines
regarding which procedures and patient populations would be best serv
ed. Previous studies have failed to determine the cost effectiveness a
nd actual reduction in homologous blood exposure attributable to intra
operative autologous transfusion in adolescents who have undergone pre
operative phlebotomy. Methods. Fifty-five adolescents (intraoperative
autologous transfusion group) who underwent posterior instrumentation
and fusion for idiopathic scoliosis with the use of an intraoperative
autologous transfusion device were compared to 50 patients (control gr
oup) who underwent the same procedure without the intraoperative autol
ogous transfusion device. Results. The average percent salvage of red
blood cells by the intraoperative autologous transfusion device was 35
%. The control group utilized significantly more of the predonated aut
ologous blood than the intraoperative autologous transfusion group (1.
34 units/ case vs. 1.78 units/case, P < 0.05). Homologous blood usage
was the same in both groups. Two patients in the intraoperative autolo
gous transfusion group required nondirected homologous blood (total of
four units), compared to three patients in the control group (total o
f four units) (P = 0.048). Using multiple regression analysis, the tot
al number of transfusions was significantly correlated with the estima
ted blood loss and the duration of surgery in both groups. Postoperati
ve hematocrit levels were slightly higher in the control group, but th
ere was not a significant difference. Conclusions. The addition of int
raoperative autologous transfusion to a preoperative phlebotomy progra
m had no benefit on homologous blood exposure or postoperative hematoc
rit changes in this population. Blood requirements for this procedure
can be met less expensively and more reliably by merely donating one's
own blood.