A retrospective survey was performed in 1994, involving 496 adult home
parenteral nutrition (HPN) cases, newly enrolled in the year 1993 fro
m 13 European countries from 75 centres. From the 8 countries having r
egistered more than 80% of cases (423 patients), incidence and prevale
nce ranged from 0.2 to 4.6 and 0.3 to 12.2 patients/10(6) population/y
ear. In the patients studied, the diagnosis was cancer (42%), Crohn's
disease (15%), vascular diseases (13%), radiation enteritis (8%), AIDS
(4%) and other nonmalignant non-AIDS diseases (18%). Short bowel synd
rome and intestinal obstruction were the two major indications for HPN
in 31% and 22%, respectively. Seventy-three percent of the centres ha
d a nutrition team. HPN was administered through a tunnelled venous ce
ntral catheter in 73%, cyclical nocturnal infusions were used in 90% o
f patients, and intravenous feeding was the sole source of nutrition i
n 33%. Only 44% undertook HPN unaided. The present report indicates th
at cancer has now become the main indication for HPN in Europe; there
was, however, a heterogeneous distribution of diseases amongst the rep
orting countries. The observed 9 (6-12)-month probability of survival
was poor in AIDS (n = 8; 12%) and cancer patients (n = 78; 29%) but be
tter for the other HPN indications (n = 115; 92%).