Bm. Goudie et al., REPEAT PRESCRIBING OF ULCER HEALING DRUGS IN GENERAL-PRACTICE - PREVALENCE AND UNDERLYING DIAGNOSIS, Alimentary pharmacology & therapeutics, 10(2), 1996, pp. 147-150
Background: The long-term use of ulcer healing drugs in the management
of dyspepsia is controversial, We have investigated repeat prescribin
g of these drugs in a general practice population. Aims: To identify t
he number of patients authorized to receive repeat prescriptions for u
lcer healing drugs, and to review the investigation status and diagnos
is in these patients. Subjects: A total of 15 495 patients registered
with eight general practitioners in seven general practices in Dundee,
UK. Methods: Case ascertainment by review of practice repeat prescrib
ing registers. Data regarding investigation and diagnosis obtained by
retrospective review of general practice case records. Results: Six hu
ndred and seventy-nine (4.4% of the total population) were authorized
to receive repeat prescriptions for ulcer healing drugs. Six hundred a
nd fifty-one (4.2%) were authorized to receive repeat prescriptions fo
r H-2-antagonists, Ranitidine was prescribed in 583 (86% of patients r
eceiving ulcer healing drugs). Endoscopy had been performed in 426 (63
%) and barium meal alone in 113 (17%); 140 (21%) had not been investig
ated, A diagnosis of peptic ulcer disease or oesophagitis was establis
hed in 382 (56%). However, 157 investigated patients (23% of all patie
nts on ulcer healing drugs) did not have a peptic diagnosis. Conclusio
ns: The prevalence of repeat prescribing of ulcer healing drugs in the
general practice population studied was 4.4%, but 44% of these patien
ts did not have a confirmed diagnosis of acid peptic disease.