ISOLATED RICE INTOLERANCE - CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS IN 4 INFANTS

We describe four infants with rice intolerance who had no hypersensiti vity to other foods. Clinical manifestations included shock, vomiting, and diarrhea, Results of tests for occult blood in stools were positi ve in all cases; results of all immunologic tests were negative, No sy mptoms were observed during 6 weeks of a diet free of rice and flour, Successive double-blind challenges caused severe shock in three of the four infants, In addition, we observed histologic alterations in the intestinal mucosa after challenge.