Nwma. Hasaniya et al., EFFICACY OF SUBCUTANEOUS SILVER-IMPREGNATED CUFFS IN PREVENTING CENTRAL VENOUS CATHETER INFECTIONS, Chest, 109(4), 1996, pp. 1030-1032
Study objectives: To determine the efficacy of an attachable subcutane
ous silver-impregnated cuff in preventing local central venous cathete
r (CVC)-related infection and catheter-related sepsis in critically il
l surgical patients, Design: A prospective analysis of the use of an a
ttachable subcutaneous silver-impregnated cuff compared with a control
group in two consecutive time periods, Setting: Two surgical ICUs at
The Queen's Medical Center at the University of Hawaii Surgical Reside
ncy Program, Honolulu, Patients: All surgical ICU patients requiring i
nsertion of central catheters, Interventions: None. Measurement and ma
in result: Two hundred thirty-five CVCs in 154 patients were prospecti
vely evaluated. Silver-impregnated cuffs were used in the first 100 ca
theters, but none were used in the remaining 135 catheters, The incide
nce of catheter-related infection in both groups was 15% and 20%, resp
ectively, not statistically significant. Catheter-related sepsis was 3
% in both groups. Conclusions: The use of an attachable subcutaneous s
ilver-impregnated cuff failed to decrease the incidence of CVC-related
infection and sepsis.