IMPROVED PREPARATION OF (R)-3-AMINOQUINUCLIDINE AND (S)-3-AMINOQUINUCLIDINE DIHYDROCHLORIDE

Authors
KOWALCZYK BA ROHLOFF JC DVORAK CA GARDNER JO
Citation
Ba. Kowalczyk et al., IMPROVED PREPARATION OF (R)-3-AMINOQUINUCLIDINE AND (S)-3-AMINOQUINUCLIDINE DIHYDROCHLORIDE, Synthetic communications, 26(10), 1996, pp. 2009-2015
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
26
Issue
10
Year of publication
1996
Pages
2009 - 2015
Database
ISI
SICI code
0039-7911(1996)26:10<2009:IPO(A(>2.0.ZU;2-H
Abstract
An improved procedure for the synthesis of either (R) or (S)-3-aminoqu inuclidine was developed. Key intermediate imine 2 was made in a one p ot process using lithium oxide as the base and molecular sieves.