AUTOGRAFTING IN CHRONIC MYELOID-LEUKEMIA - AN OVERVIEW

Autografting could become a promising treatment for patients with chro nic myeloid leukemia (CML) who cannot undergo allogeneic bone marrow t ransplantation or failed to respond to recombinant alpha-interferon (I FN). In this review, we analyze the results which have been published for patients transplanted in chronic phase and which suggest that auto grafting could prolong survival, at least in some patients. We also di scuss the different methods of purging whose clinical efficacy remains to be assessed.