HIGH IMPLANTATION AND PREGNANCY RATES WITH TESTICULAR SPERM EXTRACTION AND INTRACYTOPLASMIC SPERM INJECTION IN OBSTRUCTIVE AND NONOBSTRUCTIVE AZOOSPERMIA

Thirty-two infertile couples with obstructive and nonobstructive azoos permia were included in this study, Testicular sperm extraction (TESE) was performed in 16 obstructive azoospermic cases where microsurgical sperm aspiration (MESA) or percutaneous sperm aspiration (PESA) were impossible because of totally destroyed epididymis and 16 non-obstruct ive azoospermia cases with severe spermatogenetic defect where the tes ticles were the only source of sperm cells, A total of 288 oocytes was obtained from 32 females and 84% were injected, The fertilization rat es (FR) with 2 pronuclei (PN) and cleavage rate were 50.8 and 68.2% re spectively, A total of 15 pregnancies was achieved (53% per embryo tra nsfer), nine from the obstructive and six from the non-obstructive gro up, Four pregnancies resulted in clinical abortion (26.6%). The ongoin g pregnancy rate was 39.2% per embryo transfer (ET) and 34.3% per star ted cycle, A high implantation rate was also achieved (26.6% in nonobs tructive and 30% in obstructive azoospermia group), Using testicular s permatozoa in combination with ICSI in both obstructive and non-obstru ctive azoospermic groups, high implantation and pregnancy rates can be achieved.