A. Rajasekaran et al., SYNTHESIS AND LOCAL-ANESTHETIC EVALUATION OF SOME NEW MANNICH-BASES DERIVED FROM ALPHA,BETA-UNSATURATED KETONE, Indian Journal of Heterocyclic Chemistry, 5(3), 1996, pp. 243-244
Mannich bases were synthesised by reacting an alpha,beta-unsaturated k
etone with different secondary amines in presence of paraformaldehyde.
The title compounds have been tested for their local anesthetic actio
n in experimental animals.