Kb. Johnson et al., DISCHARGING PATIENTS WITH PRESCRIPTIONS INSTEAD OF MEDICATIONS - SEQUELAE IN A TEACHING HOSPITAL, Pediatrics, 97(4), 1996, pp. 481-485
Objective. This study measures the incidence of discrepancies among wr
itten prescriptions, medication regimens transcribed onto patient disc
harge instruction sheets (DCIs), and labels on medications dispensed b
y community pharmacies after discharge of patients from an academic me
dical center. Methods. During a 2-month study period, we collected cop
ies of prescriptions and DCIs. We also called care givers after discha
rge and asked them to read the medication labels that were filled from
discharge prescriptions. Care givers were also asked whether they rec
eived instruction from community pharmacists. Results. Data were colle
cted on 335 prescriptions for 192 patients. Differences among the pres
criptions, DCIs, and medication labels were found for 40 (12%) of the
medications prescribed at discharge, representing 19% of the patients
studied. Nineteen prescriptions had prescriber errors in dosing freque
ncies or dosage formulations. Three prescriptions were filled with dif
ferent medication concentrations or strengths than requested. Prescrip
tions were altered by the community pharmacists for unexplained reason
s in 6 cases, whereas the DCIs and original prescriptions differed in
12 cases. Only 44% of families were counseled about proper medication
administration by their pharmacists. Conclusions. A potential for medi
cation errors exists when pediatric patients are discharged with unfil
led prescriptions. The potential may be worsened when discharge instru
ctions are created from a prescription rather than from the label of a
dispensed medication. Educational and risk-management efforts should
emphasize the importance of writing complete, legible prescriptions an
d consulting appropriate reference materials to ensure that dose formu
lations and guidelines are accurate. Whenever possible, prescriptions
should be filled before patients are discharged, so that the dispensed
medications can be reviewed, and health care providers can provide ac
curate discharge instructions.