Y. Nakazato et al., IDIOPATHIC VENTRICULAR-FIBRILLATION INITIATED BY A SHORT-COUPLED VENTRICULAR PREMATURE BEAT, Japanese Heart Journal, 37(2), 1996, pp. 265-269
We report the case of a 38-year-old man who had idiopathic ventricular
fibrillation (VF) which initiated by abnormally short-coupled ventric
ular premature beats. VF was successfully prevented by the combination
of pilsicainide, propranolol, and verapamil. In particular, the effec
ts of pilsicainide are assumed to exert an important effect in control
ling this arrhythmia. Class Ic drugs may be effective for preventing V
F initiated by short-coupled VPBs.