IOBITRIDOL-250 VS IOHEXOL-240 IN PHLEBOGRAPHY OF THE LOWER-LIMBS - A DOUBLE-BLIND CLINICAL-TRIAL

Iobitridol 250 (Xenetix 250) was compared with iohexol 240 (Onmipaque 240) in phlebography of the lower limbs by means of a multicenter, ran domized double-blind trial in 70 patients. No significant difference w as demonstrated between the 2 groups in terms of diagnostic efficacy, image quality or clinical safety. Only minor reactions were recorded i n the 2 groups, essentially consisting of mild or moderate heat sensat ions. The only insufficiently informative examinations were not due to the contrast agent. Iobitridol 250 therefore appears to be a well-tol erated contrast medium, suitable for use in phlebography of the lower limbs.