Adenoviruses are ubiquitous viruses, commonly causing ocular infection
s. They are also known to cause multisystem infections. External ocula
r infections caused by adenovirus are most often due to contaminated s
ecretions. We report a patient in whom genitourinary symptoms develope
d and subsided along with ocular symptoms. Adenovirus was isolated on
ocular culture. This is the first reported case of concurrent adenovir
al keratitis and hemorrhagic cystitis. Eliciting a history of genitour
inary and respiratory symptoms is important in patients with ocular ad
enoviral infections.