RAPID RESOLUTION OF NECROLYTIC MIGRATORY ERYTHEMA AFTER GLUCAGONOMA RESECTION

A 55-year-old man presented with an 11-year history of necrolytic migr atory erythema and glossitis. After the patient's serum glucagon was d emonstrated to be elevated, computed tomography scan revealed a mass i nvolving the head of the pancreas. The patient underwent a Whipple-typ e pancreatico-duodenectomy and his rash resolved completely 6 days aft er tumor resection. He received no adjuvant treatment. A discussion of the varying theories regarding the pathogenesis and treatment of gluc agon-associated necrolytic migratory erythema is presented. (C) 1996 W iley-Liss, Inc.