PODACYCLINE-A AND PODACYCLINE-B, 2 CYCLIC-PEPTIDES IN THE LATEX OF JATROPHA-PODAGRICA

Authors
VANDENBERG AJJ HORSTEN SFAJ KETTENESVANDENBOSCH JJ BEUKELMAN CJ KROES BH LEEFLANG BR LABADIE RP
Citation
Ajj. Vandenberg et al., PODACYCLINE-A AND PODACYCLINE-B, 2 CYCLIC-PEPTIDES IN THE LATEX OF JATROPHA-PODAGRICA, Phytochemistry, 42(1), 1996, pp. 129-133
Citations number
17
Categorie Soggetti
Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
42
Issue
1
Year of publication
1996
Pages
129 - 133
Database
ISI
SICI code
0031-9422(1996)42:1<129:PAP2CI>2.0.ZU;2-4
Abstract
Two novel cyclic peptides were isolated from the latex of Jatropha pod agrica, which we named podacycline A and B. Podacycline A is a cyclic nonapeptide with the sequence Gly1-Leu2-Leu3-Gly4-Ala5-Val6-Trp7-Ala8- Gly9-Gly1. The sequence of podacycline B, a cyclic heptapeptide, was d etermined to be Phe1-Ala2-Gly-3-Thr4-Ile5-Phe6-Gly7-Phe1. The amino ac id residues of both compounds were found to have the L-configuration.