2 CASES OF DIABETIC MASTOPATHY WITH EPITH ELIOID FIBROBLASTS MIMICKING AN INVASIVE LOBULAR CARCINOMA

Two cases of diabetic mastopathy are reported. The patients presented with a rapidly increasing mammary mass. The pathologic findings of dia betic mastopathy usually consist of a lymphocytic lobulitis, a dense s tromal fibrosis and prominent epithelioid fibroblasts. In our two case s, the latter-findings were initially misinterpreted as malignant cell s of an invasive lobular carcinoma. These lesions were first described in longstanding insulin dependent diabetics but recent reports showed that they could also occur in patients with other auto-immune disorde rs (systemic lupus erythematous, hypothyroidism). Diabetic mastopathy may recurr locally and the treatment remains to be determined.