The history of the identification of the so-called (fronto-)temporal l
obe contusion is reviewed. Treatment of minor head injuries actually s
tarts with the right diagnosis. Injuries of the temporal lobe, charact
erized by a comparatively long period of post-traumatic amnesia should
be distinguished from minor head injuries (cerebral concussion). Trea
tment of minor head injuries should include good information and expla
nation of the medical aspects of minor head injuries to prevent the so
called post-concussional syndrome, with long lasting sequelae. Change
s of neurotransmitter metabolism in various kinds of head injuries hav
e been known for many years. Treatment with precursors of neurotransmi
tters (particularly physostigmine and L-DOPA) can be useful in unconsc
iousness and amnestic syndromes.