The structures of the components of large and complex viruses, determi
ned over the past year, have demonstrated the great variation in the w
ays in which viruses achieve their goals. The structure of the blueton
gue virus coat protein provides clues as to how a T=13 particle is ass
embled and the structure of the tick-borne encephalitis envelope prote
in suggests a new way of exposing a membrane fusion peptide at the rig
ht moment.