GENETIC ALGORITHMS FOR PROTEIN-STRUCTURE PREDICTION

Genetic algorithms are a general class of search methods that mimic na tural gene-based optimization mechanisms. Mutation, cross-over and rep lication operations are performed on strings. When applied to structur e prediction, each string describes a particular conformation of a pro tein molecule. There are many ways in which such search methods may be implemented. Recent results show potential for helping with protein s tructure prediction, but more data are needed before a complete assess ment can be made.