CATALYSIS OF DNA CLEAVAGE BY LANTHANIDE COMPLEXES WITH NUCLEOPHILIC OR INTERCALATING LIGANDS AND THEIR KINETIC CHARACTERIZATION

Authors
RAMMO J HETTICH R ROIGK A SCHNEIDER HJ
Citation
J. Rammo et al., CATALYSIS OF DNA CLEAVAGE BY LANTHANIDE COMPLEXES WITH NUCLEOPHILIC OR INTERCALATING LIGANDS AND THEIR KINETIC CHARACTERIZATION, Chemical communications, (1), 1996, pp. 105-107
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
1
Year of publication
1996
Pages
105 - 107
Database
ISI
SICI code
1359-7345(1996):1<105:CODCBL>2.0.ZU;2-9
Abstract
The catalysis of plasmid ds-DNA cleavage by lanthanoid cations and the ir complexes is characterized by saturation kinetics; addition of poly amines or cryptand does not hinder catalysis, which can be enhanced to a total factor of 10(7) by alcoholic co-substrates such as glycerol, or by intercalating ligands.