AMINO ALCOHOL EFFECTS ON THE RUTHENIUM(II)-CATALYZED ASYMMETRIC TRANSFER HYDROGENATION OF KETONES IN PROPAN-2-OL

Authors
TAKEHARA J HASHIGUCHI S FUJII A INOUE S IKARIYA T NOYORI R
Citation
J. Takehara et al., AMINO ALCOHOL EFFECTS ON THE RUTHENIUM(II)-CATALYZED ASYMMETRIC TRANSFER HYDROGENATION OF KETONES IN PROPAN-2-OL, Chemical communications, (2), 1996, pp. 233-234
Citations number
17
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
2
Year of publication
1996
Pages
233 - 234
Database
ISI
SICI code
1359-7345(1996):2<233:AAEOTR>2.0.ZU;2-8
Abstract
A ruthenium(II) complex generated in situ from [(RuCl2(eta(6)-C(6)Me(6 ))}(2)], (1S,2S)-2-methylamino-1,2-diphenylethanol and KOH serves as a n efficient catalyst for asymmetric transfer hydrogenation of acetophe none derivatives in propan-2-ol to give (S)-enriched alcohols in up to 92% ee and in > 90% yield.