ALIPHATIC VS AROMATIC C-H BOND ACTIVATION OF PHENYLCYCLOHEXANE CATALYZED BY CYTOCHROME P450CAM

Authors
ENGLAND PA ROUCH DA WESTLAKE ACG BELL SG NICKERSON DP WEBBERLEY M FLITSCH SL WONG LL
Citation
Pa. England et al., ALIPHATIC VS AROMATIC C-H BOND ACTIVATION OF PHENYLCYCLOHEXANE CATALYZED BY CYTOCHROME P450CAM, Chemical communications, (3), 1996, pp. 357-358
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
3
Year of publication
1996
Pages
357 - 358
Database
ISI
SICI code
1359-7345(1996):3<357:AVACBA>2.0.ZU;2-5
Abstract
Catalytic hydroxylation of phenylcyclohexane 1 by wild-type and the Y9 6A and Y96F mutant forms of cytochrome P450cam occurs only at the 3- a nd 4-positions on the cyclohexane ring, giving cis-3-phenylcyclohexano l 2, cis-4-phenylcyclohexanol 3 and trans-4-phenylcyclohexanol 4.