STEREOSELECTIVE SYNTHESIS OF 2-ARYLOXY ACIDS FROM LACTAMIDE DERIVED ESTERS OF RACEMIC ALPHA-HALO CARBOXYLIC-ACIDS

Authors
DEVINE PN DOLLING UH HEID RM TSCHAEN DM
Citation
Pn. Devine et al., STEREOSELECTIVE SYNTHESIS OF 2-ARYLOXY ACIDS FROM LACTAMIDE DERIVED ESTERS OF RACEMIC ALPHA-HALO CARBOXYLIC-ACIDS, Tetrahedron letters, 37(16), 1996, pp. 2683-2686
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
16
Year of publication
1996
Pages
2683 - 2686
Database
ISI
SICI code
0040-4039(1996)37:16<2683:SSO2AF>2.0.ZU;2-#
Abstract
Pyrolidine derived (S)-lactamide auxiliaries mediate a highly stereose lective coupling reaction between racemic alpha-haloacids and aryloxid es. These amide auxiliaries exhibit enhanced rates of reaction as well as increased degrees of diasteroselection over conventional ester aux iliaries. Copyright (C) Elsevier Science Ltd.