NEW CHIRAL PHOSPHINAMIDE CATALYSTS FOR HIGHLY ENANTIOSELECTIVE REDUCTION OF KETONES

Authors
GAMBLE MP STUDLEY JR WILLS M
Citation
Mp. Gamble et al., NEW CHIRAL PHOSPHINAMIDE CATALYSTS FOR HIGHLY ENANTIOSELECTIVE REDUCTION OF KETONES, Tetrahedron letters, 37(16), 1996, pp. 2853-2856
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
16
Year of publication
1996
Pages
2853 - 2856
Database
ISI
SICI code
0040-4039(1996)37:16<2853:NCPCFH>2.0.ZU;2-H
Abstract
A novel class of recoverable and highly stable phosphinamide catalysts for the asymmetric reduction of ketones by borane is described. Enant iomeric excesses of up to 92% have been obtained using 10 mol% of the optimum catalyst. Copyright (C) 1996 Elsevier Science Ltd.