ABSENT INHIBITION OF HEPATITIS-B VIRUS-REPLICATION BY AZIDOTHYMIDINE TN PATIENTS CHRONICALLY COINFECTED BY HIV-1 AND HBV

Authors
GALLIAN P DELAMBALLERIE X LEHUCHER MP DHIVER C RAVAUX I
Citation
P. Gallian et al., ABSENT INHIBITION OF HEPATITIS-B VIRUS-REPLICATION BY AZIDOTHYMIDINE TN PATIENTS CHRONICALLY COINFECTED BY HIV-1 AND HBV, The New microbiologica, 19(2), 1996, pp. 167-169
Citations number
4
Categorie Soggetti
Microbiology
Journal title
The New microbiologica
ISSN journal
11217138 → ACNP
Volume
19
Issue
2
Year of publication
1996
Pages
167 - 169
Database
ISI
SICI code
1121-7138(1996)19:2<167:AIOHVB>2.0.ZU;2-F
Abstract
The effect of Azidothymidine (AZT) in vivo on the replication of the H epatitis B Virus (HBV) was studied in a population of 25 patients chro nically coinfected by HBV and Human Immunodeficiency Virus Type 1 (HIV -1), and receiving AZT at the usual dosage. The drug effect was evalua ted by sequential measurement of the HBV DNA level. No significant act ivity at short and medium term was found on HBV replication in either homosexuals or IV drug users chronically coinfected by HIV-1 and HBV.