INTRACYSTIC APPLICATION OF MEBENDAZOLE SOLUTION IN THE TREATMENT OF LIVER HYDATID-DISEASE - PRELIMINARY-REPORT OF 2 CASES

Mebendazole, a derivate of benzimidazole, is commonly used for the tre atment of hydatid disease in patients at high operative risk and/or to prevent secondary hydatidosis. In this study, 2 cases of liver hydati d disease, in which mebendazole was used both orally and for intracyst ic application are presented. These cases have been treated by percuta neous drainage and videolaparoscopic methods. Mebendazole solution at a concentration of 2.4 mu g/ml was injected into the cyst. For a perio d of 6 months 50 mg/kg/day oral treatment was given. At the end of a 6 - to 9-month period, the total recovery was observed. This is the firs t report of mebendazole pair-treatment in the literature.