ABRUPT CESSATION OF IMMUNOSUPPRESSION IN A PATIENT WITH PERSISTENT ACUTE LYMPHOBLASTIC-LEUKEMIA FOLLOWING ALLOGENEIC TRANSPLANTATION

Authors
RYMES NL MURRAY JA HOLMES JA
Citation
Nl. Rymes et al., ABRUPT CESSATION OF IMMUNOSUPPRESSION IN A PATIENT WITH PERSISTENT ACUTE LYMPHOBLASTIC-LEUKEMIA FOLLOWING ALLOGENEIC TRANSPLANTATION, Clinical and laboratory haematology, 18(1), 1996, pp. 45-46
Citations number
10
Categorie Soggetti
Hematology
Journal title
Clinical and laboratory haematology → ACNP
ISSN journal
01419854
Volume
18
Issue
1
Year of publication
1996
Pages
45 - 46
Database
ISI
SICI code
0141-9854(1996)18:1<45:ACOIIA>2.0.ZU;2-X
Abstract
A 20-year-old man with acute lymphoblastic leukaemia (ALL) in second c omplete remission underwent sibling donor transplant, Post-transplant there was haematological and immunophenotypic evidence of persisting d isease. Cyclosporine was abruptly discontinued and following this the leukaemic clone disappeared. Discontinuation of immunosuppression may be of benefit in leukaemia which persists following transplant.