Background. The concept of lung volume reduction for generalized emphy
sema was proposed by Brantigan and associates in 1958 and reintroduced
by Cooper and colleagues in 1994. The present study presents lessons
learned from an 18-month experience. Methods. From August 1, 1994, to
August 1, 1995, 53 patients underwent lung volume reduction at Emory U
niversity for generalized emphysema. There were 17 women and 36 men ra
nging in age from 55 to 75 years. The length of stay ranged from 10 to
59 days. At the time of presentation, 47 patients were receiving oxyg
en and 35 were receiving steroids. Forty-six patients were operated on
using a median sternotomy and 7 through a unilateral thoracotomy. All
patients underwent preoperative and postoperative pulmonary rehabilit
ation. Results. There was one early death and four late deaths. Lesson
s learned from this group of patients are presented. Conclusions. Lung
volume reduction surgery remains a sea of relatively uncharted waters
, with the future direction yet to be determined.