Sp. Fischer et al., KETOROLAC AND PROPOFOL ANESTHESIA IN A PATIENT TAKING CHRONIC MONOAMINE-OXIDASE INHIBITORS, Journal of clinical anesthesia, 8(3), 1996, pp. 245-247
There is continued controversy regarding the concurrent use of monoami
ne oxidase inhibitors (MAOIs) and opioids in anesthesia. MAOIs are bei
ng used in both psychiatry and also in the treatment of Parkinson's di
sease. The adverse interaction of meperidine with MAOIs is well descri
bed in the literature. Several other opioids used in anesthesia have b
een reported as potentially safe and also implicated in interaction wi
th MAOIs. We present a case report using ketorolac as a nonopioid anal
gesic during a general anesthesia combined with midazolam and propofol
in a successful approach in a patient continuing MAOI therapy.