J. Neuerburg et al., IN-VITRO EVALUATION OF VENA-CAVA FILTERS, RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 164(4), 1996, pp. 331-337
Purpose: In vitro clot-trapping capacity of 16 different caval filters
should be evaluated under varying experimental conditions. Material a
nd methods: In a flow model simulating in vivo conditions (soft latex
tube, dextran solution at 37 degrees C, pulsatile flow at a mean rate
of 31/min) the efficiency of 16 caval filters was evaluated in horizon
tal and vertical position by using 640 or 1280 clots/filter (8 sizes).
Non-self centering filters were tested in centric and in tilted posit
ion. Results: Efficiency of optimally centered caval filters varied be
tween 97.8 and 69.4 %. The largest thrombi were captured by all optima
l centered filters. A change from vertical to horizontal position of t
he flow model resulted in a variation of filter efficiency by about 4.
8 %. Efficiency of non-self centering filters decreased significantly
when placed in a tilted position (mean decrease 15.5 %; range 2.7 % -
37.7 %) resulting in a deterioration of the capture rate by as much as
43.2 %. Conclusion: Under optimal study conditions efficiency of all
evaluated caval filters was high. Tilting of caval filters resulted in
a significant efficiency decrease.