PRODUCTION OF (R)-1-PHENYLETHANOL THROUGH ENANTIOSELECTIVE OXIDATION OF (S)-ISOMER FROM THEIR RACEMIC-MIXTURE BY PACHYSOLEN-TANNOPHILUS IFO-1007

Authors
HASEGAWA Y UOSAKI H ADACHI S MATSUNO R
Citation
Y. Hasegawa et al., PRODUCTION OF (R)-1-PHENYLETHANOL THROUGH ENANTIOSELECTIVE OXIDATION OF (S)-ISOMER FROM THEIR RACEMIC-MIXTURE BY PACHYSOLEN-TANNOPHILUS IFO-1007, Biotechnology letters, 18(4), 1996, pp. 367-372
Citations number
5
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
18
Issue
4
Year of publication
1996
Pages
367 - 372
Database
ISI
SICI code
0141-5492(1996)18:4<367:PO(TEO>2.0.ZU;2-A
Abstract
Stereoselective oxidation of (S)-isomer of rac-1-phenylethanol (1-PA) by the yeast Pachysolen tannophilus IFO 1007 immobilized into calcium alginate gels was investigated to produce (R)-isomer. Continuous produ ction of (R)-isomer was accomplished for more than 80 h with an enanti omeric excess of > 90% using a bioreactor of a fluidized-bed type.