HORMONAL AND RECEPTORS STATUS OF BREAST-CANCER PATIENTS WITH PREGNANCY, LACTATION AND AFTER PREGNANCY ABORTION

Patients with breast cancer that was diagnosed during pregnancy have r evealed substantial disturbances in the hormonal status after abortion or labour. An elevation of estradiol, testosterone, progesterone in t he serum levels is observed most frequently, the androgens/estrogens r atio is considerably disturbed, the urine excretion of nonclassic phen olsteroids is increased. The revealed disturbances are more frequent i n the patients with rapidly progressing disease, fatal end and in the patients with metastases to regional lymph nodes. The revealed disturb ances can be used as prognosis criteria after mastectomy.