Dr. Fleming et al., LYMPHOCYTE INFUSION FOR DELAYED EXTRAMEDULLARY RELAPSE OF ACUTE-LEUKEMIA FOLLOWING BONE-MARROW TRANSPLANTATION, Leukemia & lymphoma, 21(5-6), 1996, pp. 525-528
We report a case of extramedullary relapse of acute myelogenous leukem
ia twelve years after allogeneic bone marrow transplantation. Due to t
he localized nature of the relapse, we were able to eliminate a majori
ty of the tumor burden, utilizing local irradiation. Destined with eve
ntual systemic leukemia relapse, further therapy utilizing donor lymph
ocytes was given at a time of minimal disease burden. The patient rema
ins in a state of complete remission.