New infectious diseases and microorganisms continue to be described Th
ey may be blood- or arthropod-borne, or spread by the respiratory sexu
al or faecal-oral route; in some cases, modes of transmission remain u
nknown or new ones have been described. Complex factors have contribut
ed to the re-emergence of older pathogens in both developing and devel
oped countries. Changes in medical and surgical practice have led to t
he frequent description of resistant gram-positive and negative bacter
ia, fungi and bacteria. Although many of the newly described agents ma
y not be directly relevant to routine anaesthetic and intensive care p
ractice, their impact on both patients and staff can be minimized by a
dherence to rational infection control guidelines, understanding of lo
cal disease and anti-microbial resistance patterns, sensible patient e
valuation and access to expert advice. Given recent history, it can be
expected that new microorganism; and clinical syndromes will continue
to appear.