CORONARY-ARTERY BYPASS-GRAFTING WITHOUT CARDIOPULMONARY BYPASS AND WITHOUT INTERRUPTION OF NATIVE CORONARY FLOW USING A NOVEL ANASTOMOSIS SITE RESTRAINING DEVICE (OCTOPUS)
C. Borst et al., CORONARY-ARTERY BYPASS-GRAFTING WITHOUT CARDIOPULMONARY BYPASS AND WITHOUT INTERRUPTION OF NATIVE CORONARY FLOW USING A NOVEL ANASTOMOSIS SITE RESTRAINING DEVICE (OCTOPUS), Journal of the American College of Cardiology, 27(6), 1996, pp. 1356-1364
Objective. This study assessed the feasibility of coronary artery bypa
ss grafting on the beating heart without interruption of native corona
ry blood flow using a novel anastomosis site restraining device. Backg
round. Recently, an end-to-side bypass technique was described that do
es not require interruption of flow in the recipient artery. Methods.
By means of a suction device (''Octopus''), in 31 pigs the epicardium
was grasped and immobilized through an arm contraption fixed to the op
erating table. In the first 15 consecutive pigs (study I), the two-dim
ensional motion of an epicardial beacon was monitored. In 16 subsequen
t pigs (study II), an internal mammary artery was grafted under the mi
croscope in two steps to a proximal coronary artery segment, without c
ardiopulmonary bypass. First, the internal mammary artery was sutured
end-to-side to the outside of the coronary artery. Secondly, an orific
e was punched in the partitioning coronary wall by an excimer laser ca
theter introduced through a temporary side-branch of the internal mamm
ary artery. Results. Study II: During 43 suction periods in four anast
omosis areas, immobilization,was achieved for 15 to 169 min (>30 h in
total) in 13 open- and 9 closed-chest procedures without hemodynamic d
eterioration, The area circumscribed by the edges of the beacon trajec
tory (area in which the anastomosis is to be tracked) was reduced from
73.0 +/- 43.0 mm(2) (mean +/- SD) to 1.3 +/- 0.5 mm(2) (p < 0.001) in
the open-chest and to 0.2 +/- 0.2 mm(2) in the closed-chest procedure
. At 6 weeks, no myocardial or coronary suction lesions were found. St
udy II: Nonocclusive anastomosis surgery required 25 +/- 3 min. No lea
kage, serious arrhythmias, graft closure or hemodynamic deterioration
occurred during the procedure or for 2 h after ligating the coronary a
rtery proximally. At 6 weeks, all seven grafts were patent. Conclusion
s. Coronary bypass on the beating heart without interruption of corona
ry how is feasible. In both open- and in closed-chest procedures, the
''Octopus'' reduced anastomosis site motion to about 1 x 1 mm without
adverse consequences.