Many surgeons consider the ileoanal pouch procedure to be the procedur
e of choice for patients who require surgery for ulcerative colitis an
d familial adenomatous polyposis. To determine long-term results, 460
patients (mean+/-SD age, 31+/-9 years) who underwent the ileoanal pouc
h procedure from 1980 through 1991 were prospectively observed by comp
uterized registry. The leading indication for operation was ulcerative
colitis (n=382; 83%). A J-shaped reservoir was created in 434 patient
s (94%). More than 5 years after ileostomy closure, the mean number of
bowel movements was 5.8+/-2.2, and 13% of patients had leakage. Most
patients (94%) were satisfied with their results. Sixteen patients (3.
5%) required recreation of a permanent stoma for pouch failure. Compli
cations (major and minor) occurred in 266 patients (58%) and included
obstruction (n=94; 20%), pouch fistula (n=26; 6%), anastomotic strictu
re (n=40; 9%), anastomosis separation (n=14; 3%), and pouchitis (n=83;
18%). Modifications in technique and increased operative experience h
ave significantly decreased the incidence of obstruction (P=.05) and p
ouch-related complications (P=.004). Despite complications, long-term
results are acceptable, and patient satisfaction remains high.