N. Dekimpe et al., REARRANGEMENT OF 5-(BROMOMETHYL)-1-PYRROLINIUM SALTS INTO FUNCTIONALIZED PIPERIDINES, Tetrahedron letters, 37(18), 1996, pp. 3171-3174
5-(Bromomethyl)-1-pyrrolinium bromides undergo rearrangement with alko
xides in the corresponding alcohol to afford 2,5-dialkoxypiperidines,
which are easily converted into 3-alkoxypiperidines. 2,5-Dialkoxypiper
idines undergo a peculiar thermal rearrangement to afford 5-alkoxy-1,2
,3,4-tetrahydropyridines. Copyright (C) 1996 Elsevier Science Ltd