M. Cheney, POSTMARKET SURVEILLANCE TO DETERMINE NUTRITIONAL IMPACT OF MACRONUTRIENT SUBSTITUTES, Regulatory toxicology and pharmacology, 23(1), 1996, pp. 22-24
The nutritional impact of a macronutrient substitute can only be deter
mined after the substitute has been approved for use in foods and ther
e is widespread use by the population over time. Modeling and experime
ntal studies have predictive value, but they cannot replace real life
in which the choice of foods is influenced by labeling and advertising
aimed at promoting consumption on the basis of reduced sugar, fat, an
d/or energy. impacts could include alterations in the energy distribut
ion of the diet and changes in the intakes of essential nutrients, For
this reason, postmarket surveillance (PMS) of consumption patterns of
macronutrient substitutes has been proposed as a condition of approva
l of macronutrient substitutes and/or extending permitted uses. PMS sh
ould be conducted on a representative sample of the population, should
allow comparisons over time, and should collect data on food consumpt
ion patterns, nutrient intakes, and frequency of consumption of macron
utrient substitutes. This is a more detailed and costly form of PMS th
an measuring actual product consumption. (C) 1996 Academic Press, Inc.