MORPHOLOGICAL AND FUNCTIONAL ALTERATIONS OF NAILFOLD CAPILLARIES IN APATIENT WITH DERMATOMYOSITIS

Citation
T. Klyscz et al., MORPHOLOGICAL AND FUNCTIONAL ALTERATIONS OF NAILFOLD CAPILLARIES IN APATIENT WITH DERMATOMYOSITIS, Hautarzt, 47(4), 1996, pp. 289-293
Citations number
21
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
ISSN journal
00178470
Volume
47
Issue
4
Year of publication
1996
Pages
289 - 293
Database
ISI
SICI code
0017-8470(1996)47:4<289:MAFAON>2.0.ZU;2-O
Abstract
We report on a 70-year-old female patient with dermatomyositis. The co nnective tissue vascular bed was studied with capillaroscopy to evalua te morphological and functional changes of skin capillaries. Capillaro scopic findings showed morphological alterations such as rarefication of capillaries, avascular fields and tortuosity of nailfold capillarie s. In addition, fluorescence-videomicroscopy showed pathologically inc reased transcapillary diffusion of dye in the apex region of nutritive skin capillaries. Increased capillary leakage probably contributed to the developement of oedema in our patient. Immunosupressive therapy c ombined with intensified manual lymphatic drainage was successful.